Amphetamine is known to produce increased wakefulness and focus during a time of decreased fatigue and appetite. Amphetamines are used to treat ADHD, symptoms of traumatic brain injury, and daytime drowsiness. However, there are other potent drugs that are associated with amphetamine such as met methamphetamine, levoamphetamine, and dextroamphetimine. Amphetamine affects the neurotransmitters that have to do with the reward experience. This neurotransmitter mostly being dopamine; however in the regions of the brain that form new memories, such as the hippocampus, the drug does not affect dopamine.
Most of the time, amphetamines would be considered an agonist because it increases the levels of dopamine, serotonin, and norepinephrine throughout specific parts of the brain. However, a recent study has suggested that amphetamines are both agonists and antagonists. This is because when the amphetamine is released into the body, it acts on a protein that is a part of the DAT (the dopamine transporter). By acting on this protein, it not only causes the dopamine levels to increase, but it is also inhibits the reuptake of dopamine.
Amphetamines have been found to contain specific proteins that he brain already creates naturally, causing the number of these proteins to raise. The presence of amphetamines most directly affects Phenylalanine and β-Phenethylamine, which are formed in the peripheral nervous system as well as in the brain itself. These molecules are thought to modulate levels of excitement and alertness.
When used correctly, amphetamine can be a very useful drug. However, it is being used in many ways that was not intended. Many gangs use it to create an artificial high for a short period of time. Tolerance is developed rapidly in amphetamine abuse, thereby the amount of the drug that is needed to satisfy the addiction needs to be increased at regular intervals. This is how the addiction that many users have today is created. If an addiction is created, the user needs to take a different drug that also increases the amount of dopamine levels so that it feels as if the amphetamine is still being used. However, with the use of a different drug to create the same effects, the user won't feel it necessary anymore to Tolerance is developed rapidly in amphetamine abuse, thereby the amount of the drug that is needed to satisfy the addiction needs to be increased at regular intervals. But when amphetimen is used correctly, it does many wonderful things. The main thing that it does is that it increases alertness when the patient is either drowsy, depressed, ill, etc.
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